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1

Germ line selection against point mutations in mitochondrial DNA

James B. Stewart⁎, Camilla Koolmeister, Christoph Freyer, Nils-Göran Larsson

Journal:

Year:

2011

Language:

english

File:

PDF, 70 KB

english, 2011

2

A Convenient Microwave-Assisted Propylphosphonic Anhydride (T3P ® ) Mediated One-Pot Pyrazolone Synthesis

Desroses, Matthieu, Jacques-Cordonnier, Marie-Caroline, Llona-Minguez, Sabin, Jacques, Sylvain, Koolmeister, Tobias, Helleday, Thomas, Scobie, Martin

Journal:

European Journal of Organic Chemistry

Year:

2013

Language:

english

File:

PDF, 586 KB

english, 2013

3

Vinylic MIDA Boronates: New Building Blocks for the Synthesis of Aza-Heterocycles

Llona-Minguez, Sabin, Desroses, Matthieu, Ghassemian, Artin, Jacques, Sylvain A., Eriksson, Lars, Isacksson, Rebecka, Koolmeister, Tobias, Stenmark, Pål, Scobie, Martin, Helleday, Thomas

Journal:

Chemistry - A European Journal

Year:

2015

Language:

english

File:

PDF, 555 KB

english, 2015

4

Pinacolyl Boronic Esters as Components in the Petasis Reaction.

Tobias Koolmeister, Mikael Soedergren, Martin Scobie

Journal:

Year:

2002

File:

PDF, 26 KB

2002

5

The First Example of Chiral Induction Using Homochiral Boronic Esters in the Petasis Reaction.

Tobias Koolmeister, Mikael Soedergren, Martin Scobie

Journal:

Year:

2002

File:

PDF, 27 KB

2002

6

ChemInform Abstract: A Versatile New Synthetic Route to 1N-Hydroxyindazoles.

Fredrik Lehmann, Tobias Koolmeister, Luke R. Odell, Martin Scobie

Journal:

Year:

2010

File:

PDF, 64 KB

2010

7

The first example of chiral induction using homochiral boronic esters in the Petasis reaction

Tobias Koolmeister, Mikael Södergren, Martin Scobie

Journal:

Tetrahedron Letters

Year:

2002

Language:

english

File:

PDF, 114 KB

english, 2002

8

Pinacolyl boronic esters as components in the Petasis reaction

Tobias Koolmeister, Mikael Södergren, Martin Scobie

Journal:

Tetrahedron Letters

Year:

2002

Language:

english

File:

PDF, 317 KB

english, 2002

9

Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission

Freyer, Christoph, Cree, Lynsey M, Mourier, Arnaud, Stewart, James B, Koolmeister, Camilla, Milenkovic, Dusanka, Wai, Timothy, Floros, Vasileios I, Hagström, Erik, Chatzidaki, Emmanouella E, Wiesner,

Journal:

Nature Genetics

Year:

2012

Language:

english

File:

PDF, 508 KB

english, 2012

10

A versatile synthesis of diverse 3,4-fused cinnolines via the base-catalysed condensation of 2-amino-2?-nitrobiaryls

Slevin, ?sa, Koolmeister, Tobias, Scobie, Martin

Journal:

Chemical Communications

Year:

2007

Language:

english

File:

PDF, 378 KB

english, 2007

11

A facile and efficient synthesis of tetrahydro-β-carbolines

Desroses, Matthieu, Koolmeister, Tobias, Jacques, Sylvain, Llona-Minguez, Sabin, Jacques-Cordonnier, Marie-Caroline, Cázares-Körner, Armando, Helleday, Thomas, Scobie, Martin

Journal:

Tetrahedron Letters

Year:

2013

Language:

english

File:

PDF, 2.14 MB

english, 2013

12

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Gad, Helge, Koolmeister, Tobias, Jemth, Ann-Sofie, Eshtad, Saeed, Jacques, Sylvain A., Ström, Cecilia E., Svensson, Linda M., Schultz, Niklas, Lundbäck, Thomas, Einarsdottir, Berglind Osk, Saleh, Aljo

Journal:

Year:

2014

Language:

english

File:

PDF, 11.30 MB

english, 2014

13

835: Inhibiting MTH1 kills cancer cells by preventing sanitisation of oxidised dNTP pool

Warpman Berglund, U., Gad, H., Jemth, A.S., Koolmeister, T., Gokturk, C., Pham, T., Nilsson, J., Eshtad, S., Scobie, M., Helleday, T.

Journal:

European Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 71 KB

english, 2014

14

A Versatile New Synthetic Route to 1 N -Hydroxyindazoles

Lehmann, Fredrik, Koolmeister, Tobias, Odell, Luke R., Scobie, Martin

Journal:

Organic Letters

Year:

2009

Language:

english

File:

PDF, 259 KB

english, 2009

15

POLRMT does not transcribe nuclear genes

Kühl, Inge, Kukat, Christian, Ruzzenente, Benedetta, Milenkovic, Dusanka, Mourier, Arnaud, Miranda, Maria, Koolmeister, Camilla, Falkenberg, Maria, Larsson, Nils-Göran

Journal:

Year:

2014

Language:

english

File:

PDF, 3.97 MB

english, 2014

16

Rational design and validation of a Tip60 histone acetyltransferase inhibitor

Gao, Chunxia, Bourke, Emer, Scobie, Martin, Famme, Melina Arcos, Koolmeister, Tobias, Helleday, Thomas, Eriksson, Leif A., Lowndes, Noel F., Brown, James A. L.

Journal:

Scientific Reports

Year:

2014

Language:

english

File:

PDF, 5.13 MB

english, 2014

17

240 The combination of Chk-1 and ATR inhibitor synergistically kills cancer cells

Sanjiv, K., Hagenkort, A., Reaper, P.M., Koolmeister, T., Mortusewicz, O., Schultz, N., Scobie, M., Berglund, U.W., Charlton, P.A., Pollard, J.R., Helleday, T.

Journal:

European Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 62 KB

english, 2014

18

Chemical strategies for development of ATR inhibitors

Llona-Minguez, Sabin, Höglund, Andreas, Jacques, Sylvain A., Koolmeister, Tobias, Helleday, Thomas

Journal:

Expert Reviews in Molecular Medicine

Year:

2014

Language:

english

File:

PDF, 657 KB

english, 2014

19

The amino terminal extension of mammalian mitochondrial RNA polymerase ensures promoter specific transcription initiation

Posse, V., Hoberg, E., Dierckx, A., Shahzad, S., Koolmeister, C., Larsson, N.-G., Wilhelmsson, L. M., Hallberg, B. M., Gustafsson, C. M.

Journal:

Nucleic Acids Research

Year:

2014

Language:

english

File:

PDF, 1.41 MB

english, 2014

20

Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities

Sanjiv, Kumar, Hagenkort, Anna, Calderón-Montaño, José Manuel, Koolmeister, Tobias, Reaper, Philip M., Mortusewicz, Oliver, Jacques, Sylvain A., Kuiper, Raoul V., Schultz, Niklas, Scobie, Martin, Char

Journal:

Year:

2016

Language:

english

File:

PDF, 4.70 MB

english, 2016

21

ChemInform Abstract: A Facile and Efficient Synthesis of Tetrahydro-β-carbolines.

Desroses, Matthieu, Koolmeister, Tobias, Jacques, Sylvain, Llona-Minguez, Sabin, Jacques-Cordonnier, Marie-Caroline, Cazares-Koerner, Armando, Helleday, Thomas, Scobie, Martin

Journal:

Year:

2013

File:

PDF, 32 KB

2013

22

ChemInform Abstract: A Convenient Microwave-Assisted Propylphosphonic Anhydride (T3P®) Mediated One-Pot Pyrazolone Synthesis.

Desroses, Matthieu, Jacques-Cordonnier, Marie-Caroline, Llona-Minguez, Sabin, Jacques, Sylvain, Koolmeister, Tobias, Helleday, Thomas, Scobie, Martin

Journal:

Year:

2014

File:

PDF, 33 KB

2014

23

ChemInform Abstract: Vinylic MIDA Boronates: New Building Blocks for the Synthesis of Aza-Heterocycles.

Llona-Minguez, Sabin, Desroses, Matthieu, Ghassemian, Artin, Jacques, Sylvain A., Eriksson, Lars, Isacksson, Rebecka, Koolmeister, Tobias, Stenmark, Paal, Scobie, Martin, Helleday, Thomas

Journal:

Year:

2015

File:

PDF, 30 KB

2015

24

Validation and development of MTH1 inhibitors for treatment of cancer

Warpman Berglund, U., Sanjiv, K., Gad, H., Kalderén, C., Koolmeister, T., Pham, T., Gokturk, C., Jafari, R., Maddalo, G., Seashore-Ludlow, B., Chernobrovkin, A., Manoilov, A., Pateras, I. S., Rasti, A

Journal:

Annals of Oncology

Year:

2016

Language:

english

File:

PDF, 771 KB

english, 2016

25

Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities

Sanjiv, Kumar, Hagenkort, Anna, Calderón-Montaño, José Manuel, Koolmeister, Tobias, Reaper, Philip M., Mortusewicz, Oliver, Jacques, Sylvain A., Kuiper, Raoul V., Schultz, Niklas, Scobie, Martin, Char

Journal:

Year:

2016

Language:

english

File:

PDF, 5.66 MB

english, 2016

26

Corrigendum: MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Gad, Helge, Koolmeister, Tobias, Jemth, Ann-Sofie, Eshtad, Saeed, Jacques, Sylvain A., Ström, Cecilia E., Svensson, Linda M., Schultz, Niklas, Lundbäck, Thomas, Einarsdottir, Berglind Osk, Saleh, Aljo

Journal:

Year:

2017

Language:

english

File:

PDF, 107 KB

english, 2017

27

Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors

Llona-Minguez, Sabin, Höglund, Andreas, Ghassemian, Artin, Desroses, Matthieu, Calderón-Montaño, José Manuel, Burgos Morón, Estefanía, Valerie, Nicholas C. K., Wiita, Elisee, Almlöf, Ingrid, Koolmeist

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 3.23 MB

english, 2017

28

ATM/Wip1 activities at chromatin control Plk1 re‐activation to determine G2 checkpoint duration

Jaiswal, Himjyot, Benada, Jan, Müllers, Erik, Akopyan, Karen, Burdova, Kamila, Koolmeister, Tobias, Helleday, Thomas, Medema, René H, Macurek, Libor, Lindqvist, Arne

Journal:

The EMBO Journal

Year:

2017

Language:

english

File:

PDF, 1.44 MB

english, 2017

29

Structure–metabolism-relationships in the microsomal clearance of piperazin-1-ylpyridazines

Llona-Minguez, Sabin, Ghassemian, Artin, Baranczewski, Pawel, Desroses, Matthieu, Koolmeister, Tobias, Artursson, Per, Scobie, Martin, Helleday, Thomas

Journal:

Year:

2017

Language:

english

File:

PDF, 3.08 MB

english, 2017

30

Correction to Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors

Llona-Minguez, Sabin, Höglund, Andreas, Ghassemian, Artin, Desroses, Matthieu, Calderón-Montaño, José Manuel, Burgos Morón, Estefanía, Valerie, Nicholas C. K., Wiita, Elisee, Almlöf, Ingrid, Koolmeist

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 316 KB

english, 2017

31

Mitogen-activated protein kinases MPK4 and MPK12 are key components mediating CO 2 -induced stomatal movements

Tõldsepp, Kadri, Zhang, Jingbo, Takahashi, Yohei, Sindarovska, Yana, Hõrak, Hanna, Ceciliato, Paulo H.O., Koolmeister, Kaspar, Wang, Yuh-Shuh, Vaahtera, Lauri, Jakobson, Liina, Yeh, Chung-Yueh, Park,

Journal:

The Plant Journal

Year:

2018

Language:

english

File:

PDF, 1.04 MB

english, 2018

32

Modulation of mtDNA copy number ameliorates the pathological consequences of a heteroplasmic mtDNA mutation in the mouse

Filograna, R., Koolmeister, C., Upadhyay, M., Pajak, A., Clemente, P., Wibom, R., Simard, M. L., Wredenberg, A., Freyer, C., Stewart, J. B., Larsson, N. G.

Journal:

Science Advances

Year:

2019

Language:

english

File:

PDF, 2.04 MB

english, 2019

33

TEFM regulates both transcription elongation and RNA processing in mitochondria

Jiang, Shan, Koolmeister, Camilla, Misic, Jelena, Siira, Stefan, Kühl, Inge, Ramos, Eduardo Silva, Miranda, Maria, Jiang, Min, Posse, Viktor, Lytovchenko, Oleksandr, Atanassov, Ilian, Schober, Florian

Journal:

Year:

2019

Language:

english

File:

PDF, 1.75 MB

english, 2019

34

Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria

Nicholls, Thomas J., Spåhr, Henrik, Jiang, Shan, Siira, Stefan J., Koolmeister, Camilla, Sharma, Sushma, Kauppila, Johanna H.K., Jiang, Min, Kaever, Volkhard, Rackham, Oliver, Chabes, Andrei, Falkenbe

Journal:

Year:

2019

Language:

english

File:

PDF, 6.74 MB

english, 2019

35

Development of a chemical probe against NUDT15

Zhang, Si Min, Desroses, Matthieu, Hagenkort, Anna, Valerie, Nicholas C. K., Rehling, Daniel, Carter, Megan, Wallner, Olov, Koolmeister, Tobias, Throup, Adam, Jemth, Ann-Sofie, AlmlÃ¶f, Ingrid, Loseva

Journal:

Nature Chemical Biology

Year:

2020

File:

PDF, 5.83 MB

2020

36

FBXL 4 deficiency increases mitochondrial removal by autophagy

Alsina, David, Lytovchenko, Oleksandr, Schab, Aleksandra, Atanassov, Ilian, Schober, Florian A, Jiang, Min, Koolmeister, Camilla, Wedell, Anna, Taylor, Robert W, Wredenberg, Anna, Larsson, NilsâGÃ¶r

Journal:

EMBO Molecular Medicine

Year:

2020

File:

PDF, 1.25 MB

2020

37

Proofreading deficiency in mitochondrial DNA polymerase does not affect total dNTP pools in mouse embryos

Sharma, Sushma, Koolmeister, Camilla, Tran, Phong, Nilsson, Anna Karin, Larsson, Nils-GÃ¶ran, Chabes, Andrei

Journal:

Nature Metabolism

Year:

2020

File:

PDF, 1.34 MB

2020

38

Novel Broad-Spectrum Antiviral Inhibitors Targeting Host Factors Essential for Replication of Pathogenic RNA Viruses

Tampere, Marianna, Pettke, Aleksandra, Salata, Cristiano, Wallner, Olov, Koolmeister, Tobias, Cazares-KÃ¶rner, Armando, Visnes, Torkild, Hesselman, Maria Carmen, Kunold, Elena, Wiita, Elisee, KalderÃ©

Journal:

Year:

2020

File:

PDF, 24.90 MB

2020

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